Co-Investigator, Health and Retirement Study
Contact Information
515 Delaware Street SE, Room 1-136 Moos Tower
MMC 609
Minneapolis, MN 55455
Phone: 612-624-1257
E-mail: thya0003@umn.edu
Education
Ph.D., University of Minnesota, Minneapolis, 2004
M.P.H., University of Minnesota, Minneapolis, 2000
M.B.B.S., Grant Medical College, 1998
Research and Projects
Dr. Thyagarajan is director of the Division of Molecular Pathology and Genomics, and a faculty investigator in the Advanced Research and Diagnostic Laboratory (ARDL). The MDL processes some 25,000 specimens annually related to inherited and infectious diseases, bone marrow engraftment, and blood and solid tumor malignancies. Thyagarajan and his MDL colleagues are implementing next-generation DNA sequencing (NGS) for diagnosing genetic disease.
Selected Recent Publications
. Associations of Age, Sex, Race/Ethnicity and Education with 13 Epigenetic Clocks in a Nationally Representative US Sample: The Health and Retirement Study. The Journals of Gerontology: Series A . 2021;76(6):1117-1123. doi:10.1093/gerona/glab016.
. Pre-Analytical Variables Influencing Stability of Blood-Based Biomarkers of Neuropathology. Journal of Alzheimer's Disease. Forthcoming. doi:10.3233/JAD-230384.
Immune cells are associated with mortality: the Health and Retirement Study. Frontiers in immunology. 2023;14:1280144. doi:10.3389/fimmu.2023.1280144.
. Epigenetic-based age acceleration in a representative sample of older Americans: Associations with aging-related morbidity and mortality. PNAS. 2023;120(9):e2215840120. doi:10.1073/pnas.2215840120.
Age-related differences in T cell subsets and markers of subclinical inflammation in aging are independently associated with type 2 diabetes in the Health and Retirement Study. Canadian Journal of Diabetes. 2023;47(7):594-602.e6. doi:10.1016/j.jcjd.2023.05.010.